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Here, by looking into these genetic and epigenetic modifications in the PDGF pathway, we found this pathway to be significantly targeted by changes in copy number.
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To assess whether the prioritization process is predicting BRCA1 ESEs that are more likely to be targeted by sequence changes, we determined the percentage colocalization of predicted ESEs with reported sequence changes in BIC before and after increasing the ESEfinder threshold, considering the location relative to exon ends and taking into account evolutionary sequence conservation (Table 4).
Just as interesting as who was targeted by these changes is who wasn't targeted.
"The argument that these lower standards apply to aliens ignores the fact that our Bill of Rights protects persons not citizens; that it is important for law enforcement and intelligence agencies to have the trust and cooperation of the communities who will feel most targeted by these changes".
This allows it to more selectively curate its own list of "winners and losers" in terms of which companies will be targeted by the changes.
A review investigating application of theory using the 19-item 'Theory Coding Scheme' (Michie & Prestwich, 2010), found that only 10% of studies of theory-based interventions reported links between behaviour change techniques and theoretical constructs and only 9% reported that all the constructs had been targeted by behaviour change techniques.
These results robustly indicate that at least one-fifth of the hEIR genes are frequently targeted by inactivating genetic changes in the examined cancers, which notion encouraged further functional analysis of hEIR genes in a reductionist MCF10A model of epithelial tumorigenesis.
"We were specifically targeted by the Facebook changes in their news feed algorithm.
The economic divide between smokers has led some to suggest that poorer Australians will be unfairly targeted by the tax changes.
Hence, the constructed network clusters complemented the results of our GO analysis by facilitating detailed insight into the molecular pathways targeted by carcinogenic expression changes.
Analysis of differentially expressed molecules in the context of known signalling pathways enables identification of molecular networks targeted by observed expression changes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com