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This latter possibility suggests that, in mice fed a high fat diet, hepatic gene expression patterns can be used to gauge inflammation intensity, and that targeted analytical methods can be developed to exploit this information to gain insight into the tissue remodeling that accompanies excessive intake of dietary fat.
Considering that false-positive signals are possible, these findings warrant further investigations through (a) targeted analytical safety studies to formally assess these safety signals and (b) additional analysis of other international SRSs to assess the degree of overlap across databases, and finally confirm the actual value of national SRSs in signal detection.
If the maximum concentration in the calibration standards was exceeded, then samples were diluted gravimetrically to within the targeted analytical range.
For platform screening data and targeted analytical data, we used 50,000 and 1,000 trees, respectively.
The targeted analytical approach verifies the findings obtained by the non-targeted metabolite profiling.
Do MYC2-mediated changes in the herbivore-induced transcriptome translate into a wider spectrum of defense secondary metabolites, apart from alkaloids already demonstrated by targeted analytical approach?
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As for this discipline, the steps for the systematic validation of AD biomarkers need to target analytical validity, clinical validity, and clinical utility.
In particular, the results add weight to the suggestion that interventions targeting analytical, ruminative processing in ED may augment existing interventions (Park et al., in press).
The agreement between the pre-test predictions, the developed layered-target analytical model, and the experiments is good.
To assist in the vessel design, two- and three-layered target analytical models were developed to predict the penetration of depleted uranium rods striking at velocities up to 2 km/s into layered targets of ceramic (boron carbide and silicon carbide) and aluminum, beryllium and steel alloys.
Querci et al. [ 10] developed a real-time PCR based ready-to-use multi-target analytical system for simultaneous identification of 39 GM events by using event-specific, construct-specific and species-specific primers and probe combinations.
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