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The first branch is untargeted vs. targeted analysis.
The candidate gene targeted analysis allowed the combination of cost effectiveness with a hypothesis-based approach.
That said, the list of metabolites that did not pass the test (Data S2 in File S2) may provide a guide for designing future quantitative targeted analysis.
To this end, targeted analysis of metabolites could provide valuable data on sample stability.
This will allow a gene targeted analysis aimed to identify BSP-associated polymorphisms in Romagnola.
For those families in which the WAS mutation is known, targeted analysis of the WAS gene is recommended.
We then summarized our results within the context of existing literature to generate hypotheses for future targeted analysis.
Targeted analysis period and targeted trajectories.
Targeted analysis focuses on known compounds, often to quantitate changes, for example in response to stress or disease.
Targeted analysis of the SWATH-MS data confirmed these results.
Targeted analysis of metabolites has been used to functionally validate protein expression changes.
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