Sentence examples for targeted analyses from inspiring English sources

For highly targeted analyses (that is, selected genomic regions such as gene promoters, or validation of targeted regions from whole methylome analyses), traditional approaches of pyrosequencing or Sanger sequencing still predominate [ 8- 11].

Method validation is however often omitted in plant metabolome studies, as the well-established methodologies for classical targeted analyses such as recovery optimization cannot be strictly applied.

Moreover, most metabolic targets were identified from their increased expression in tumor transcriptomic studies, or from targeted analyses looking at the metabolic impact of particular oncogenes or tumor suppressors on selected metabolic pathways.

For targeted analyses, the product scan MS mode was used to monitor the fragmentation patterns of the following ions: m/z 353 for caffeoyl-quinic acid and caffeoyl-isocitric acid, m/z 337 for coumaroyl-quinic acid and coumaroyl-isocitric acid and finally m/z 367 for feruloyl-quinic acid and feruloyl-isocitric acid.

Channelling of data from this comprehensive approach to targeted analyses allowed us to unravel the impact of the phytohormone ABA on metabolic regulation.

We also performed targeted analyses in a single cohort in the Southeastern US to characterize relationships between NIDU and HAART utilization in this setting.

Despite the increasing use of MS-based metabolite profiling, it has only been combined with NAF in a limited number of studies, basically to unravel the subcellular location of primary metabolites in soybean leaves and potato tubers by means of targeted analyses [20], [28], [29].

As revealed by these and other studies, which include comparing genomes assembled from different individuals and targeted analyses, the total number of inversion regions in the human genome is now close to 500 (http://projects.tcag.ca/variation/), but this figure will likely increase with deep sequencing data coming from the 1000 genomes project (www.1000genomes.org).org

There his research focuses on improving the identification of unknown chemicals in environmental samples using non-targeted analyses.

Next, we demonstrate the applicability of RP-HILIC to studies of a wide range of compounds in non-targeted analyses through the simultaneous separation of peptides and PNGaseF-released glycan chains from deglycosylated glycoproteins.

As it is unlikely that this gene can be identified by candidate gene approaches based solely on sequence similarity to the genes reported in the bibliography, these results emphasize the advantage of using non-targeted analyses based on correlation rather than more targeted gene approaches based solely on homology with genes previously described as being associated with a given process.