Similar tumor-specific RSV targeting was noted previously in mice harboring PC-3 derived xenograft tumor [ 7].
Following depletion of RPL11, significant increase in transcripts of all three targets was noted with the most notable increase (16.2-fold) seen for p21.
On the other hand, a reduced risk for missing LDL-C targets was noted in the presence of ischemic heart disease (OR 0.6), diabetes (0.5), higher statin doses, ezetimibe treatment, or specialist care, respectively.
Known EIN3 targets are noted by asterisks; all other EIN3 candidate targets were discovered by this study.
The most significantly counted canonical pathway is indicated for each miRNA along with the P-value of enrichment in Table 2, and relevant targets are noted in Figure 2. Targets of the signature miRNAs were enriched for Wnt/ β-catenin canonical signalling pathway (Table 2).
No recurrence in the target knee was noted.
Gliosis outside the target structures was noted in patients 1, 9, 11 and 14.
During each run, the rank of the "target gene" was noted.
A clear cell-to-cell contact between immune effector cells and tumour target cells was noted in biopsies during immunotherapy, Figure 4. We also studied the influence of intratumoural lymphocyte subsets on survival.
A trend toward a higher mean nocturnal time within target range was noted for closed- versus open-loop therapy, although not reaching statistical significance (5.3 vs. 3.2 h, P = 0.12).
