These two TFs were our targets to validate the method we developed to measure the activity of TFs in cells.
By studying a panel of these targets to validate the results, we found that estradiol stimulation triggered the association of c-Myb with promoters and that association correlated with increased target gene expression.
One compound TALA with the highest affinity was isolated for further in vitro pharmacodynamic validation and target identification to validate the screen results.
Furthermore, we provide experimental results for a variety of benchmarks which intensively exercise the main components (CPU, Memory, HDDs, and NICs) of the target platforms to validate the accuracy of the equipment in terms of power dissipation and energy consumption.
From both the organizations, respondents were selected with an equal mix of experience, gender, seniority and target group to validate the instrument under the discretion of hospital authority.
Another constraint limiting direct imaging strategy is the necessity to develop a specific probe for each molecular target and then to validate the sensitivity, specificity, and safety of each probe for specific applications before their introduction into the clinic.
Training targets are the database of surface reflectance functions from which basis functions are generated and test targets are used to validate the performance of the device.
The Astex diverse dataset [24], comprising high resolution protein ligand complexes with drug like molecules and pharmaceutically relevant protein targets, was used to validate the PADIF approach for pose prediction.
The authors have selected different targets to validate different aspects of the method (CD45, FN1 and Dscam1) but their major figure describing SeqZip method highlights the strong bias to underrepresent mRNA isoforms that require multiple ligation events.
Total six cases with various target CBCs are investigated to validate the proposed method.
