Sentence examples for target to trigger from inspiring English sources

Moreover, Noxa was recently shown to be a p73 target to trigger E1A-induced apoptosis in p53 deficient cells [ 57].

This suggests that in the absence of [Vrn2], the [Vrn1] target to trigger VS was 0·74.

This is the pharmacophore concept, based upon steric and electronic features that permit optimal interaction with a specific biologic target to trigger or block the target's biologic response.,, The p-i hypothesis has been derived from experimental work with T cell clones and TCR-transfected hybridomas expressing drug-specific receptors.

In addition senior executives will have to hit diversity targets to trigger bonuses and it is aiming for 20% of all staff to be BAME by 2020.

The main application concerns diffusion in cellular biology, where we compute as an example the distribution of arrival times of calcium ions to small hidden targets to trigger vesicular release.

If the subjective response (appearance of symptoms) of test subjects is able to discriminate between exposure to test chemicals and placebos, in a blinded design, this would suggest the operation of a toxicological mechanism in which culpable agents interact with tissue targets to trigger a receptor-mediated pathophysiological response.

"The blood data collected before 2009 were used for target purposes to trigger follow-up urine tests for EPO detection," it said.

The strategy is, upon target accumulation, to trigger tPA release from a prodrug construct by a usual heparin dose.

The recognition domain at the 3′ terminus of the sensing probe hybridizes with target miRNAs to trigger EXPAR with exponential signal amplification.

Using p53 gene as the target model to trigger the molecular machine operation, cyclic nucleic acid strand displacement polymerization (CNDP) was specifically induced, leading to the DNAzyme mediated catalytic reaction for signal readout.

In this work, we propose a new strategy that only employs one target DNA to trigger multiple catalyzed hairpin assembly (CHA) reactions and sticky ends self-assembly to prepare hundreds of nanometer-sized DNA nanoparticles.