Moreover, the identified transcriptional networks that are disturbed might be pharmaceutically targeted to reconstitute impaired spermatogenesis in men with YCMD offering potential for male infertility treatment.
As crystallization targets became more complex it has proved possible to reconstitute and solve the structure of entirely recombinant spliceosomal subunits (U1 snRNP [ 6]) as well as large, multi-domain proteins and their complexes (Prp8 [ 9 ] and Brr2 [ 10,11,12 ]).
The endothelium is a chief target of sepsis-induced events, and clinical outcome in septic patients is largely dependent on the ability to reconstitute damaged endothelium.
Phosphorylated oligonucleotides were designed to reconstitute the 160 base pair fragment and insert an AloI restriction site directly into the target sequence region.
In the approach described here, a targeting vector that contains exon 1 of the hprt gene along with a specific transgene is used to reconstitute Hprt activity in Hprt negative ES cells.
Our results demonstrate the feasibility of targeting CCR5 in primary T cells using an engineered megaTAL nuclease, and the potential to use gene-modified cells to reconstitute a patient's immune system and provide protection from HIV infection.
The second was to reconstitute the church.
I had to reconstitute my memories.
He may even be tempted to reconstitute his government.
