Sentence examples for target to delay from inspiring English sources

In conclusion, our findings strongly support the relevance of CD151 as a potential therapeutic target to delay breast cancer progression.

Each of them could serve as a biomarker for disease progression and each represents a preventive or therapeutic target to delay or prevent tumorigenesis.

Our results provide experimental evidence of the important role of GPR30 in the development of tamoxifen resistance, establishing a new therapeutic target to delay drug resistance or improve response to endocrine treatment in cases that develop tamoxifen resistance.

The findings from this study provide additional evidence that CD151 acts to enhance tumor formation initiated by a range of oncogenes and strongly support its relevance as a potential therapeutic target to delay breast cancer progression.

The aging issue in HD is of importance since, if cellular defects related to "normal" aging are risk factors for HD, they could constitute interesting therapeutic targets to delay disease onset and slow progression.

In practice, we implement the idea by simply introducing multiple intermediate (virtual) components in between the regulator and its targets to delay the signal transduction.

Factors that increase the expression of MMPs and VEGF have been suggested as potential therapeutic targets to delay or reduce the joint destruction that occurs in RA patients [ 31].

In addition, during G2/M, Hog1 targets Hsl1 to delay cell-cycle progression via the inhibitory phosphorylation of Cdc28 by Swe1 (Clotet et al. 2006; Duch et al. 2012).

Therefore, increased doses could be a strategy to provide higher and more persistent plasma concentration and thus to improve the efficacy against the target parasites and to delay the development of anthelmintic resistance in goat parasites.

It may be used in the routine clinical assessment of patients with cancer (particularly due to its strict connection with cachexia and poor performance status), suggesting that inflammation is a further therapeutic target, potentially able to delay the onset of cachexia and/or death in cancer patients.

The mRNA expression of the Bcl-2 family gene BNIP3, an HIF1- α target linked to delayed neuronal death through stabilization of p53 tumor suppressor during chronic hypoxia, was reduced.