Sentence examples for target to confer from inspiring English sources

Therefore, ERCC1 is an attractive target to confer increased cellular sensitivity to cisplatin-based chemotherapy.

In the last twenty years, modification of starch has been highlighted by food scientists as a primary target to confer added value on cereal products for both nutritional and industrial uses [ 7].

The potential for any drug resistant mutation in either target to confer cross-resistance to other medications in the respective inhibitor class also raises a significant impediment to selecting optimal therapies.

Nevertheless the chemical industries nowadays are increasingly involved in specialty chemicals (small quantity, batch production, high added value) as well as formulated products (complex mixtures targeted to confer specific end-use properties).

Thus, NUAK1 may have no additional effect on genomic stability and instead regulate other targets to confer a growth advantage to the cells.

Excitingly, clinical and pre-clinical studies have suggested Plk1, Aurora A and Wip1 as promising drug targets to confer enhanced cancer therapy, consistent with the role of these kinases in checkpoint recovery, mitosis, and other processes.

Distal enhancers physically contact target promoters to confer high level transcription.

We developed Stress Transcription Factor Identification Algorithm (STFIA), which integrates these two kinds of high throughput genome-scale data (gene expression and TF-gene association data) to identify plausible stress TFs that regulate the target genes to confer stress protection.

This study provides preclinical evidences of miR-148a and miR-216a target site insertions to confer adenoviral selectivity and proposes 8-miR148aT an an optimal detargeting strategy for genetically-engineered therapies against PDAC.

Target genes known to confer resistance to first and second-line drugs were amplified and the amplicons sequenced.

The presence of mutations in target genes known to confer resistance with high confidence indicated that 95.1% (98/103) of the atypical XDR Beijing isolates were resistant to at least 10 anti-TB drugs: isoniazid, rifampin, ethambutol, pyrazinamide, streptomycin, amikacin, kanamycin, capreomycin, ethionamide, and ofloxacin.