Sentence examples for target suitability from inspiring English sources
While useful, the so-called CRAVED approach also leaves much unspecified about the relative importance of relationships among the different dimensions of target suitability.
Therefore, chromobodies enable new functional studies and may provide valuable information concerning target suitability at a very early stage of drug development.
However, the uncertainties regarding the activation mechanism, and the observation of paradoxical activation rather than inhibition of the yeast enzyme by ATP-competitive inhibitors, have placed a question mark over its suitability as a target.
Furthermore, their need for regular recharging (typical battery lifetime of less than a week) hinders their suitability for target groups that are uncomfortable with managing modern technologies.
In the current study, we used the adenosine A3 receptor (A3R) as a sample target to validate the suitability of the used system and the experimental approaches.
In the course of discussing different target types for their suitability in the European Spallation Source (ESS) one main focus was on neutronics' performance.
The challenge for future studies will be to reveal the suitability of targeting Myc for breast cancer treatment, either by direct inhibition or by indirectly targeting another pathway.
The high saturation magnetization of the meso-silica coated magnetite particles suggests their suitability for targeted drug delivery applications.
While substantial increase in the amount of impervious surface was allowed to occur, no meaningful negative impact was brought about on the land suitability of targeted land-uses.
These conserved sites were further analyzed in terms of secondary structure, hydrophilicity and solvent-accessible surface to determine their suitability for targeting anti-peptide antibodies/anti-viral therapies.
Nine such regions were identified and analyzed for structural properties like surface exposure, hydrophilicity and residue type to evaluate their suitability for targeting an anti-peptide antibody/anti-viral response.
