Sentence examples for target significant from inspiring English sources

In addition, micro RNAs that target significant numbers of genes changed in expression in db/db GEC were found, including for example mir-26a, which is a potential regulator of 18 of the 267 genes.

These data are consistent with the assumption that anti-CD19 therapy would probably target significant fractions of PCs while not enhancing all PCs.

Because of the propensity of these patients towards capillary leak and thus a greater risk of ARDS and cerebral oedema, our own management approach is to target significant hypovolaemia with concurrent tissue hypoperfusion, that is, clinical markers of organ dysfunction (e.g. oliguria) with biochemical markers (e.g. lactate and central venous oxygen saturation).

Under the new rules, the EU would use the same anti‑dumping methodology for all WTO members, and target "significant market distortions", i.e. where prices are not market-based.

Rio is targeting significant debt reduction in 2014.

Their gains have come not by broadening their appeal but rather by targeting significant resources at marginal seats.

"They [extremists] are trying to create a panic in the society" by targeting significant people, says Zia Rahman, a professor of criminology at the University of Dhaka.

"As flagged in our investor update we have targeted significant cost reductions by the end of 2017," a spokeswoman for HSBC told Reuters, confirming the content of the staff email.

While Section 702 forbids the intentional targeting of Americans or people inside the United States – a practice known as "reverse targeting" – significant amounts of Americans' phone calls and emails are swept up in the process of collection.

Before prosecutors approve such tactics, the previously undisclosed guidelines require that they consider whether an operation identifies a "clearly defined" objective, whether it is truly necessary, whether it targets "significant criminal actors or entities," and other factors, the officials said.

"As flagged in our Investor Update, we have targeted significant cost reductions by the end of 2017," HSBC said in a statement.