Sentence examples for target sequential from inspiring English sources

The process is driven by 2D drug structural similarity, and target sequential similarity.

Many of the insulin-regulated sites belong to the PI3K/Akt/mTOR pathway, and phosphorylation of most of these substrates was inhibited by MK2206 and LY294002, reflecting that these inhibitors target sequential proximal steps in the canonical insulin signaling pathway.

In the first case an HLA-B8-restricted CTL response was generated against an emerging mutant epitope in the HIV p17 Gag region and in the second, HLA-A2-restricted CTL responses targeted sequential epitope variants in reverse trancriptase of HIV-Pol.

The target permits sequential analysis of unique samples using these two instruments (see Methods section).

We have focused on using the adaptive process at a single treatment time point to identify a letrozole-induced essential gene as a second target for sequential therapy.

Following the hybridization of the 5'-anchor region of a guide RNA (gRNA) to the 3' end of its target message, sequential base pairing directs U insertion and deletion in a processive enzyme cascade [ 6].

In this paper, we propose a new light-weight target-activated sequential payload (TASP) HT model that performs packet inspection and injects faults to create a new type of DoS attack.

To tackle this issue, we have developed JaSPEx-MLS: a software-based automatic parallelization framework targeted at sequential irregular Java/JVM applications, that is based on Method-Level Speculation and Software Transactional Memory, and works atop the OpenJDK HotSpot JVM, a state-of-the-art managed runtime.

As a result no P. falciparum mutants have currently been reported where two or more genes have been targeted by sequential transfection procedureshttp:///.

For the ANOVAs, treatment assignment ('on' versus 'off'), sequential target repetitions (non-target, first AX, second AX, third AX) and trial type (AX BY, AX BX, AX AY) for each dimension (spatial and verbal) were within-subject variables.

To further increase the spectrum of mutations that can be targeted, multiple AOs could be combined as a cocktail to target blocks of sequential exons [39].