Exact(9)
A 15 bp sequence is duplicated as direct target repeats (DR) on insertion of SCCmec [6] [7].
A beta-lactamase gene ctx-m-14 with its surrounding insertion elements (ISEcp1, truncated IS903 and a 20 bp inverted repeat sequence) may compose an active transposon which is directly bordered by two putative target repeats "ATTAC".
Moreover, there are two copies of a 5 bp direct repeat "ATTAC" precisely bordering the IRL and IRR2, thus likely the target repeats generated by insertion of a transposon.
However, based on SCCmec excision experiments [7], it appears that nucleotide mutations are likely to be introduced during the insertion of SCCmec, generating target repeats that are not perfectly matched.
Thus, SKM2 predicts that near-complete hydroxylation of the FIH-accessible fraction of hydroxylatable target repeats is required for efficient, oxygen-dependent FIH-release.
These considerations make it difficult to give an estimate of a realistic concentration of FIH binding target repeats, and FIH sequestration could be much less pronounced than expected from idealised theoretical considerations.
Similar(51)
The S.E.C. can target repeat violations.
Many countries have laws against harassment or "malicious communication", but these generally target repeated actions, direct contacts and verbal or physical threats.
If you've never played, it's not rocket science: throw Frisbee at target, repeat.
In order to improve the selectivity of this method for the longer repeats, a "double probe hybridization assay" was performed in which an intermediate probe was used to replace a target repeat sequence having more than 9 repeats with a shorter sequence possessing less than 9 repeats.
Only two direct target repeat sequences, one close to the 3'-end of orfX and the other abutting the left end of WC28 SCCmec, could be detected.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com