Exact(49)
Do you think you fit the advertisers' target profiles?
Then, another Fourier series is used to represent the difference between the two target profiles.
Here, as a case study we investigate the target profiles of the popular top selling drugs in 2012 [18].
Tang et al. expanded on this algorithm to improve the computational cost and accuracy with drug screen data with little overlap between drug target profiles [60].
This polypharmacology targeting example, while highlighting specific characteristics of ALK, MET, and EGFR, may be generalizable to other kinase target profiles in several ways.
Other non-kinase polypharmacology approaches will likely be quite different, possibly involving target profiles more diverse, more rigid, or otherwise distinct from protein kinases.
Similar(11)
Blogs will be created — whatever we think this target profile will be receptive to.
"It would take only a small percentage of that target profile — affluent baby boomers — to fill this up".
The following Fig. 4 exposed the steps of constructing W-Hotelling profile for linear target profile.
The estimated target profile is seen to be indeed spatially sparse.
The target profile of a query chemical is then provided according to the ranked fusion scores.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com