"Although further opportunities for improving margins and profitability may partially mitigate these economic impacts if the current weaker economic conditions persist, the attainment of some of our medium-term financial targets, principally with regard to income related metrics, may be delayed to beyond 2014," the bank said in a statement.
Thus, the use of such mutants in combination with CD40 targeting principally allows further reduction of potential TRAIL-related side effects in cases where the latter and the apoptotic effect in the targeted tumor make differential use of TRAILR1 and TRAILR2.
His target was principally two Silwan neighbourhoods: Wadi Helweh and al-Bustan (the Garden).
On Wednesday, Pentagon officials said today, American warplanes struck in eight planned target areas, principally around Mazar-i-Sharif, Kabul and Kandahar as well as in a number of engagement zones around Afghanistan.
Although Schrems' complaints are continuing to target Facebook principally, the original Europe vs Facebook mass surveillance complaint from 2013 also referenced other U.S. tech companies that had been referenced in documents leaked by NSA whistleblower Edward Snowden as also being involved in the NSA's PRISM data collection program — including Apple, Microsoft and Yahoo.
This site was selected because the target consists principally of fly muscle, with minimal risk of damaging any internal structures/organs.
The equity of a drug target is principally evaluated by its genetic vulnerability with tools ranging from antisense- and microRNA-driven knockdowns to induced expression of the target protein.
Bacterial reporter cells (i.e. strains engineered to produce easily measurable signals in response to one or more chemical targets) can principally be used to quantify chemical signals and analytes, physicochemical conditions and gradients on a microscale (i.e. micrometer to submillimeter distances), when the reporter signal is determined in individual cells.
The observation that the network of known tip cell markers and their targets is principally intact and in fact upregulated rather than downregulated may be a reflection of the more immature vessel plexus in Nrp1 null mutants.
and insisted that refugee activists should principally target the government, which implements the detention policy.
