Sentence examples for target polymerase from inspiring English sources

Finally, the ultimate goal remains the development of efficient triphosphate prodrugs that would completely overcome the phosphorylation issues by delivering the active compound directly to the target polymerase.

A positive result was observed with primers NPhlebo2+ and ATos2, previously found to target polymerase genes of a range of phleboviruses (8 ).

They target polymerase chain reaction (PCR) amplified rRNA gene fragments, or directly retrieved community rRNA (genes) and can, at least in principle, be designed to detect any microorganism [ 26].

In fact, there are nearly 35 approved antiviral drugs that target polymerases of various pathogens [6], [7] [8], [9], [10], [11] [11].

The artificial microRNAs could efficiently inhibit the expression of the target polymerases in AFP-positive HCC cells at both RNA and protein levels, and HCC cells treated with the recombinant virus Ad/AFP-Casp-AFP-amiR exhibited significant G0/1 phase arrest.

Previously, we have reported a 16S rDNA targeted polymerase chain reaction (PCR) method for the specific detection of Salmonella serovars [J. Appl. Bacteriol. 80 (1996) 659].

Until recently, trees based on molecular data were derived from analyses of small numbers of genes, the constraint being that DNA sequences were obtained by direct sequencing involving targeted polymerase chain reaction (PCR).

An extensive survey of declining and healthy honey bee populations, using metagenomics and targeted polymerase chain reaction (PCR), helped to identify several microbial associates of CCD colonies, the most informative of which was the discistrovirus Israeli acute paralysis virus (IAPV) [4].

We searched transcriptome databases from representatives of all six genera (and in the case of Acavomonas peruviana targeted polymerase chain reaction [PCR]) for homologues of EF1A and EFL.

Ribavirin, which is a broad-spectrum inhibitor of RNA viruses and targets polymerase function, showed an even larger window of inhibition because it targets an earlier step in the life cycle.

We have combined Illumina Paired End (PE) sequencing data and targeted polymerase chain reaction (PCR) sequencing to obtain the genome-wide polymorphisms from mitochondria and chloroplast from thirteen strains of O. tauri sampled from the North West Mediterranean sea (Grimsley et al. 2010).