Sentence examples for target operator from inspiring English sources

This precisely tunes the distances between the DNA reading heads in WH1 and the C-terminal domain (WH2), to match the target operator or iteron sequences.

According to the determined crystal structure of CLldR from C. glutamicum in complex with its target operator DNA, there are four conserved amino acid residues indispensable for DNA-binding, which are also conserved in FadR.

Transcription of lytM is under the control of the WalKR system, and we have shown that WalR binds directly to its target operator sequence upstream from the lytM promoter [12], [14].

The investigation of how DNA-binding proteins search and find their targets was pioneered in the studies of lac repressor, which was shown to bind to the target operator much faster than the 3D diffusion limit.

In the crystal structure of the I-TevI DNA-binding domain bound to DNA representing either its homing target site or its target operator site, only one of the carboxy-terminal residues (Tyr242) makes a hydrogen bond to the phosphate backbone of the DNA substrate, clearly not providing any specificity to the interaction of I-TevI with its DNA substrate [ 47].

Microcalorimetric analysis of the binding of the two TtgR dimers to the cognate operator showed biphasic behavior, and an interaction model was developed for the cooperative binding of two TtgR dimers to their target operators.

Using target operators that specify the control objective, the pulse design is reduced to the maximization/minimization problem of the expectation values subject to additional requirements if needed, which can be solved by calculus of variations.

We then distinguish between: (i) targeted operators, which restrict the mutational space to specific regions of the sequence that are therefore more likely to affect the property that needs to be evolved; and (ii) oriented operators, which further specify particular mutation patterns to bias the production of variants toward the current design target.

The target speaker (operator) walks in front of the Head-and-Torso Simulator (HATS) while speaking.

A prototypic system is described here in detail: It consists of the binding of MS2 bacteriophage coat protein to its RNA recognition sequence and the interaction between the bacterial LacI repressor protein to its target lacO operator DNA sequence.

TRs allow or repress transcription in response to the presence of an effector molecule that influences their association or dis-association with their target DNA operator sequence (DOS) [ 18].