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The US Department of Energy has set a target of replacing 30% of petroleum consumption with biomass [ 2].
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These experts were in favour of replacing participation targets with targets around information provision or public understanding of screening.
The LHRH receptor targeting concept offers the possibility of replacing doxorubicin with even more potent cytotoxics, but with the advantage of increasing anticancer activity without enhancing organ toxicity.
The outcome of replacing the mandatory water conservation targets with a self-certification conservation approach was predictable.
The 17 goals were presented to the UNGA last year by an open working group of 70 countries that had been charged with producing a set of targets to replace the millennium development goals, which expire at the end of 2015.
Starting this week and continuing over the next year or so, the UN's usual Who's Who of politicians and officials from governments and international agencies will meet to draw up a new list of targets to replace the Millennium Development Goals (MDGs), which were set in September 2000 and expire in 2015.
The resulting 'Bali roadmap' is a global warming pact that starts a two-year process of negotiations designed to agree a new set of emissions targets to replace those in the Kyoto protocol.
The method can be further extended to the quantitative detection of a variety of targets by replacing the lead-responsive DNAzyme with other functional DNA.
This was achieved using Bxb1 mycobacteriophage integrase-mediated recombination to deliver transgenes into the P. falciparum genome in a site-specific manner, dictated by the presence in the parental line Dd2attB of the attB target sequence, replacing the cg6 locus (12).
EEF1A-based expression vector includes 4.1 kb upstream and 4.2 kb downstream flanking areas of the EEF1A gene, so the ORF of the of the target gene replaces the coding exons of the elongation factor 1 alpha protein in the natural EEF1A gene, mimicking with all possible accuracy the structure of the natural gene in the resulting expression plasmid.
The second design requires more machining of the targets, and replacing the targets is more complex and takes longer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com