Sentence examples for target of growth from inspiring English sources

If the innovation forward linkages are the same across sectors, there is no reason to select a specific sector as a target of growth policy.

The phenotype of the PPARβ/δ-null suggests an important role in lipid homeostasis and this protein has received attention as a downstream target of growth regulatory genes, in particular in the colon.

Because Cox-2 is a known downstream target of growth factor signalling pathways [ 12, 13], we explored the possibility that activation of iFGFR1 also induces Cox-2 expression.

Thus, even if Cdk2 is not absolutely required for cell proliferation it could serve as a central target of growth inhibitory, tumor suppressive pathways involved in preventing uncontrolled cell proliferation.

At the heart of this process is the Rb/E2F complex, itself the target of growth factors and external trophic signals and a tumor suppressor broadly inactivated in human cancers.

FoxO is a classic target of growth factor Trk receptor signaling [ 44, 45]; FoxO proteins are expressed in the detached retina [ 46]; therefore, phosphorylation of FoxO mediated by Akt may play a role in neurotrophins-mediated cell survival.

Targeting of growth factor receptors showed therapeutic potential in palliative settings for many solid tumors.

AKTs are major downstream targets of growth factor receptors that signal through phosphatidylinositol 3-kinase (Testa and Bellacosa, 2001).

Sources and targets of growth factors will be also involved in reactions of the immune system, but only under certain circumstances.

Genome-wide functional approaches such as those using small interfering RNA (siRNA) technology, supported by bioinformatics, could help strategize effective targeting of growth factors, receptors, and PTKs.

The prospects for a higher rate of cure in patients with locally advanced colorectal cancer are extremely promising, given the emerging evidence that supports therapeutic targeting of growth factors, growth-factor receptors and down-stream pathways [ 36].