Sentence examples for target of disruption from inspiring English sources

This module contains many members of the phosphatidylinositol 3-Kinase-AKT pathway, also a frequent target of disruption in glioblastoma [2].

Despite becoming obvious targets of disruption, job boards still contribute 10-15 percent of hires in the U.S. Wave 2: Active versus passive sourcing.

In this article, I explore common evolutionary themes of chemical signaling (e.g., estrogen signaling in vertebrates and phytoestrogen signaling from plants to symbiotic soil bacteria) and show that such signaling systems are targets of disruption by EDCs.

As a transducer of Hh signaling, the GPCR-like protein Smoothened (Smo) is a promising target for disruption of unregulated Hh signaling.

Recruitment is an attractive target for disruption — hundreds of billions spent every year, with inefficient business models and widely felt pain.

These render the GPCRs and ligands promising drug targets for disruption of the tumor progression cascade.

The mechanisms involved in thyroid homeostasis are numerous and complex, and there are multiple potential targets for disruption of thyroid hormone homeostasis (Schmutzler et al. 2007).

Furthermore, there is growing evidence that, in addition to the reproductive, other endocrine systems such as the hypothalamus pituitary thyroid (HPT) axis may be targets of endocrine disruption.

These tools can probe chemical biological interactions at fundamental levels, focusing on the molecular and cellular pathways that are targets of chemical disruption.

These enzymes and their pathways constitute broad categories of potential targets for disruption that could serve to enable the observed metabolic phenotypes of cancer cells (377).

Systems biology has become a key component in drug and biomarker discovery, to identify both the causative targets in disease networks in addition to potential biomarkers of target disruption.