In addition to providing a link between DNA and the spindle, kinetochores are the signaling hubs for the spindle assembly checkpoint (SAC) and the target of attachment-error correction mechanisms (Santaguida and Musacchio 2009; London and Biggins 2014; Sacristan and Kops 2015).
At about six months of age infants begin to respond socially to particular people who become the targets of attachment.
During the first two years of life, the presence of targets of attachment tends to mute infants' feelings of fear in unfamiliar situations.
Targets of attachment are usually those persons who respond most consistently, predictably, and appropriately to the baby's signals, primarily the mother but also the father and eventually others.
Infants depend on their targets of attachment not only for food, water, warmth, and relief from pain or discomfort but also for such emotional qualities as soothing and placating, play, consolation, and information about the world around them.
Colonization increased with time, with the Caco-2 cell junctions being the initial targets of attachment.
As membrane-bound lipoproteins, these archaeal ABC transporter proteins are possibly targets of phage attachment.
In vivo, FLD is a sumoylation target of SIZ1 [SAP (scaffold attachment factor, acinus, protein inhibitor of activated signal transducer and activator of transcription) and Miz1 (Msx2-interacting zinc finger), SIZ], an E3 ligase in Arabidopsis.
The first ROI (R1, Fig. 3a, see inset) was near the top of the internode close to the point of attachment of the target leaf and the second ROI (R2) was outlined on the next adjoining internode.
5 One important feature of most small GTPases are lipid modifications that are posttranslationally attached and facilitate the specific targeting and attachment of the GTPase to intracellular membranes.
