Sentence examples for target ocular from inspiring English sources

They allow the incorporation of a variety of ophthalmic pharmaceuticals to achieve therapeutic levels of drugs and bioactives at target ocular sites.

NSVs have the potential to target ocular tissues at high therapeutic value offering several favorable biological properties, such as biodegradability, biocompatibility and mucoadhesiveness, which fulfill the requirements for ophthalmic application.

Moreover, Sticky-trap remained in the eye up to 12 days, which is longer than the time periods reported in the literature for biologics targeting ocular abnormal angiogenesis.

Furthermore, to target different ocular tissues, we varied the site of ocular injection between the intravitreal space and subretinal space as we hypothesized that the area of delivery may cause different cell types to express EGFP.

The outer retina is therefore the primary target for ocular gene therapies.

New therapeutic strategies are therefore needed, particularly to target the ocular synthesis of the abnormal protein.

Interestingly, 5-LO has recently been discovered as a potential therapeutic target for ocular diseases associated with angiogenesis [ 32, 33].

VEGF has been considered to be an important pathogenic factor as well as a therapeutic target in ocular neovascularisations and associated changes [ 14].

These homoisoflavonoids are judged quantitatively in terms of statistical validation through multi-chemometric modeling approaches for the betterment and refinement of their structures required for higher antiangiogenic activity targeted to ocular neovascularization.

In this work, we studied in vitro the cellular dynamics of polyplexes, composed of a newly developed bioreducible poly amido amine) carrier, formed by polyaddition of N,N-cystamine bisacrylamide and 1-amino-4-butanol (p(CBA-ABOL)) on retinal pigment epithelium (RPE) cells, which are attractive targets for ocular gene therapy.

Thus micro-RNAs represent potential targets for ocular growth manipulation, related to myopia and/or other disorders such as scleral ectasia.