Sentence examples for target negatively from inspiring English sources

When the neurotransmitter sticks to its target, negatively charged chloride ions flow into cells, making the inside of the cells more negative, and less likely to fire.

Our results obtained in this study may be helpful in the design of drugs that target negatively charged phospholipids.

Antiphospholipid antibodies are heterogeneous, and they target negatively charged phospholipids and serum phospholipid-binding proteins.

These positively charged antimicrobial peptides target negatively charged bacterial membrane components, such as lipopolysaccharides, teichoic acids, or phospholipids.

It is its strongly cationic nature that allows this peptide to target negatively charged cancer cells with the outer membrane [ 115].

Consistently with previous findings showing Sp1-binding sites on miR-29b promoter, we found that Sp1, which is a miR-29b target, negatively regulates miR-29b: in fact, Sp1 overexpression leads to miR-29b transcriptional inhibition, whereas Sp1 silencing by shRNAs or pharmacologic inhibition by mithramycin-A increase miR-29b levels.

Conversely, the size of the expression domains of two putative targets negatively regulated by FGF signaling are dramatically increased in embryos injected with dnFGFR mRNA (Figure 3B).

Expression microarray analysis revealed 260 targets negatively regulated and 343 targets positively regulated by unliganded GR.

One of the targets negatively regulated by miR-277 is Drep-2.

Regarding the experimentally validated targets, negatively correlated ones were significantly enriched for miR-21-5p and miR-99a-5p (Table  2).

The diagnostic and prognostic roles of several autoantibodies targeting negatively charged PLs other than CL have been evaluated, though not extensively, in the setting of APS.