Our second set of research questions targeted methodological issues.
However, these findings suggest that more targeted methodological work needs to be completed in order to determine whether research utilization scores from individual participants can be 'averaged' across groups of individuals working in a similar context and still remain meaningful.
Our research shows that target choice and methodological approach are critical in differentiating these genomic events from other processes that also modify DNA sequences.
In addition to differences in treatments and target populations, two methodological factors could explain the inconsistency in findings: the method used to assign participants to treatment and the measure used to assess treatment preferences.
Factors related to the methodological quality, target disease, publication year, and study design were determined by multiple logistic regression analysis (Table 2).
The demand characteristics of these experiments, whose results are not supported by any other, converging, experimental evidence, seem particularly strong, and the work has thus been the target of particularly severe methodological criticism (Intons-Peterson & White, 1981; Banks, 1981; Thomas, 2014 p. 153).
32 The considerable variation in the prevalence of sleep disturbances may be due to the different time periods, different target populations and different methodological definitions of sleep disturbances.
The study used different methodological approaches, targeting different participants.
The design of this study targeted several clinical and methodological issues on TNF blocker dose de-escalation, including how to taper the TNF blockers, the satisfactory control condition, how to define flare, implementation in clinical practice, and the choice of the non-inferiority margin.
This chapter describes the "how to" for activities linked to the existing software architecture and target software architecture using the methodological approach to urbanization of the IT system.
