Sentence examples for target mechanism from inspiring English sources

We define the target, mechanism, and structural basis of inhibition of bacterial RNA polymerase (RNAP) by the tetramic acid antibiotic streptolydigin (Stl).

Furthermore, using this dosage we assessed mitochondrial bioenergetics and Ca2+ loading at 3 and 6 h post-injury to further verify our target mechanism and establish these assessments as a valid endpoint to use as a means to determine the therapeutic window of FCCP.

The nanocomplexes enhanced the retention time of Gd DTPA in vivo and increased the live distribution due to the passive target mechanism.

However, assessment items that include concrete, dynamic representation of abstract concepts (Wu et al. 2010) and incorporate essential variables that could draw attention to the target mechanism (Smetana and Bell 2012) are relatively scarce.

Mechanistic and functional experiments demonstrated that the beneficial effect of ceftriaxone was preserved in vivo in the presence of dihydrokainate, a EAAT2 specific transport inhibitor, indicating a key target mechanism of cetriaxone other than glutamate transporter expression regulation.

Wnt signaling is another potential target mechanism in the regulation of osteogenesis.

BACKGROUND Neuropsychiatric disorders are a leading source of disability and require novel treatments that target mechanisms of disease.

Several SNPs in genes involved in metabolism and target mechanisms of triptans have been described.

These data provide increased confidence in pursuing these target mechanisms through more detailed experimentation.

compare analysis of growth inhibition profile of NSC748393 suggested a multi-target mechanism.

Putzbach, W. et al. Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.