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As Western asset values plunged in the wake of the global financial crisis, the firm developed a "target matrix of 200 to 300 firms"; it has looked into about 100 so far.
Similarly, the projection target matrix was also reduced to 2D.
The interested reader can find further details about the target matrix in [21].
There are several possible choices for the target matrix to triangulate.
Additional file 1: Binary Drug Target matrix consisting of 727 drugs and 3,519 proteins.
Figure 6 An illustration of a target matrix assigned for L = 4 classes.
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The core idea is to first decompose a target matrix-based problem in terms of library-supported kernels, and then apply algorithmic and algebraic optimizations.
The ligand-target matrix is the core element of the chemogenomics knowledge space.
In parallel we obtained computational target predictions based on seed match, and created a miRNA-target matrix.
In parallel, for the same set of miRNAs and mRNA, a 3D miRNA-target matrix is built by examining if miRNA mRNA pairs match in the seed region.
Then, a miRNA mRNA regulatory matrix is constructed by multiplying the binary correlation matrix with the miRNA-target matrix in the dot product fashion.
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