Sentence examples for target lifespan from inspiring English sources

Tissue-specific induction of Imp-L2 appeared to selectively target lifespan and not other IIS regulated traits since, with both dilp2GAL4 and S 1 106 drivers, there was no effect on fecundity, stress resistance or 4E-BP expression (Fig. S8).

Overheating is known to be one of the major deficiencies in reaching the targeted lifespan goals.

Overall those data support the idea that the regulation of IIRc pathway by KL is conserved between C. elegans and mammals and that this pathway constitutes a relevant target for lifespan control by KL in mice.

These findings establish a novel conserved genetic target for regulating lifespan and physiology in aging animals.

The majority of compounds that increased C. elegans lifespan target mammalian proteins involved in intercellular signaling in mammals (89%).

These results suggest that neurons are a target tissue for lifespan extension and oxidative stress resistance by DAGL/ inaE overexpression.

Like a car odometer, it starts working automatically when you run, displaying the current total miles on the screen and providing an alert when you reach personal targets and shoe lifespan milestones.

However, it is not known whether these pathways ultimately converge on overlapping or distinct targets to extend lifespan.

Which of the downstream insulin signaling pathway targets mediate the lifespan extension effects of activated dSir2 and suppressed Dmp53?

Although mechanistic differences are not fully understood, one possibility is that specific pathways sensitive to dietary nutrients can be targeted to alter lifespan.

It has been proposed that CR reduces T b which in turn affects the hormonal axis that may have downstream targets that increase lifespan (Mobbs et al. 2001).