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Clinical notations of pre- and postoperative cylinder power and cylinder axis were converted to a target induced astigmatism (TIA) vector, a surgically induced astigmatism (SIA) vector, and a difference vector (DV) [ 9].
Experimental research on collapse and perforation failure at the rear surface of a concrete target induced by buried explosion of a cylindrical explosive charge was performed.
The signal transduction of most target induced strand displacement-based assays relies on the conformational changes of aptamers, significantly limiting the general applications of these sensors.
A type of "signal on" displacement-based sensors named target induced signaling probe shifting DNA-based (TISPS-DNA) sensor were developed for a designated DNA detection.
It is based on the principle that the target induced conjunction of split aptamer fragments assembled on the surface of Au nanoparticles (AuNPs).
Electrochemical aptamer (EA) sensors based on aptamer-cDNA duplex probes (cDNA: complementary DNA) and target induced strand displacement (TISD) recognition are sensitive, selective and capable of detecting a wide variety of target analytes.
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In this design, the distance of a redox tag to an electrode surface was altered as a consequence of nucleic acid target-induced conformational change in the molecular beacon (Scheme 1).
The design of signaling aptamer utilizes the target-induced switching between an aptamer/DNA duplex and an aptamer/target complex.
Fluorescence sensing mechanisms are well suited for FNAs mostly because it is easy to couple signal production based on fluorescence resonance energy transfer to target-induced structural changes of FNAs.
By combining the gold nanoparticle (AuNP) enumeration with target-induced strand-displacement reaction, we have developed a non-amplification platform for DNA and miRNA detection based on a deliberately designed sandwich-structured nanocomplex probe (SNC Probe).
Conventionally, primarily and solely spectral overlap is considered between target-induced fluorescence and paper over fluorescence.
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