Sentence examples for target for altered from inspiring English sources

Global profiling of gene expression in these tumors has revealed the nucleus-cytoskeleton-plasma membrane axis as a target for altered gene expression which determines the diversity among these tumors.

ICDH, an important rate limited enzyme in Krebs cycle, is regarded as a potential target for altered metabolism under stress [ 10].

To investigate whether loss of cellular GSH specifically rather than thiols generally is an important target for altering cytokine secretion profile, we evaluated IL-2 production in Jurkat T cells in the presence of BSO. Figure 6 confirms that IL-2 secretion from T cells is reduced in response to PHA when GSH is depleted.

The large cortical representation of the hand [10], connectivity to M1 [16], [16] and role in skilled hand movement [11] suggest that BA 5 may modulate M1 output and may therefore be an important target for altering the control of hand movement.

A potential metabolic engineering target for altering NADPH metabolism based on metabolic flux analysis is discussed.

Protein engineering revealed targets for altering substrate specificity, activity or enantioselectivity, and for changing the acid:amide ratio in the nitrilase product.

Studies in this field may identify new genes and possible targets for altering these interactions.

This pathway not only sheds light on CRF signaling by characterizing a novel, neuronal CRF initiated signaling pathway, but also reveals novel potential targets for altering the effects of CRF on a variety of behaviors.

These insights can provide the molecular targets for altering system dynamic behaviour, such as in finding treatment for diseases or in (re)engineering of cellular systems.

Other Hsp90 co-chaperones, such as FKBP51 [ 32] and CHIP [ 22], have been identified as being good targets for altering tau phosphorylation states and levels.

Our analyses reveal that E. coli has a large mutational target size for altering its antibiotic tolerance.