Sentence examples for target essential from inspiring English sources

PfHslV has no homolog in the human host and it is a promising drug target essential to the plasmodial metabolism.

It comprises brief assessments designed to target essential functions that are required for safe driving including: vision; cognition; and motor skills.

The universal requirement of RNA viruses for cellular membranes for genome replication, and the formation of membranous replication organelles with similar architecture, suggest that they target essential control mechanisms of membrane metabolism conserved among eukaryotes.

These include capsid-based candidate vaccines, and potential antivirals either in the form of glycomimetics or designer antibodies that block HBGA binding, as well as those that target essential non-structural proteins such as the viral protease and RNA-dependent RNA polymerase.

Often this is initiated by secreted toxins that mimic host proteins and functions, and usually target essential and well conserved molecules or signaling pathways.

Although the exact mechanism of DIM's anti-carcinogenic property needs further investigation, several studies seem to concur that the downstream effects of DIM are to target essential events involved in cancer cell proliferation and metastasis.

Low-power smart jamming takes a step further by targeting essential uplink control channels.

Since loss of essential genes is uniformly toxic in CRISPR-based screens, we also developed a small hairpin RNA (shRNA) library targeting essential genes.

Current treatment regimens for pancreatic ductal adenocarcinoma (PDAC) yield poor 5-year survival, emphasizing the critical need to identify druggable targets essential for PDAC maintenance.

Moreover, inhibition of autophagy using 3-methyladenine (3-MA) or small interfering RNA (siRNA) that targets essential autophagy gene ATG5 abrogated the ATPR-induced cell differentiation.

In addition, 6e showed similar inhibition potency against four serotypes of DENV, suggesting that it restrains some evolutionarily conserved targets essential for DENV replication.