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All results proved that self-targeting MTX moiety enhanced the target efficacy to potentially help the MTX-PEG-CPT NRs enter FA receptor-overexpressing HeLa cells by FA receptor-mediated endocytosis via multivalent receptor-ligand interactions [27].
The target efficacy was 95%.
The propolis extract present a multitude of constituents that can act on multiple biochemical targets affecting the balance of complex cellular networks in a way that is currently not fully understood such as the multi target efficacy model proposed by CSERMELY et al. [2].
This explains in part the multiple target efficacy exerted by plant-based products.
The overall target efficacy can be expressed by a context score.
Timing applications with ideal environmental conditions helped attract starlings to the bait lanes, increased bait consumption and target efficacy.
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S. grandiflora indeed could harbor such molecules with multiple target efficacies.
In the experiment, the targeting efficacy of the dual-targeted liposomes was compared to single-targeted liposomes to demonstrate the synergistic effect.
In silico single guide RNA (sgRNA) design is a key step for successful gene editing using the CRISPR system, and continuing efforts are aimed at refining in silico sgRNA design with high on-target efficacy and reduced off-target effects.
Indeed, the integral binding avidity plays a predominant role in the targeting efficacy; the higher integral binding avidity increases the targeting efficacy.
Figure 3 Schematic representation of PS-QD micelles and evaluation of their targeting efficacy.
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