The findings suggest that future cage designs may be modulated to target desired mechanical strain regimes at physiological loads.
Controlling aggregation using a mechanistic approach may allow improved design of therapeutic protein stability, as a complement to existing design strategies that target desired protein structures and function.
One obvious advantage of the Tev-mTALEN platform is the monomeric nature, simplifying design requirements to target desired sequences.
Both the TALEN and the CRISPR/Cas systems allow for the construction of highly efficient nucleases that target desired sequences more easily than the ZFN system.
This strategy provides a potential means of eliminating unintended expression (e.g., cryptic background patterns) and/or undesirable expression (e.g., fine-tuning promoters that target desired cell types as well as other tissues).
A multi-variable model predictive control (MPC) was formulated to solve control problems associated with a combination of regulation and targeting desired set-points.
Next-generation sequencing has still not reached its full potential due to the technical inability of effectively targeting desired genomic regions of interest.
In order to achieve an aptamer nanoparticle bio-conjugate capable of targeting desired cells, the binding protocol must preserve the biological activity of the aptamer (Balamurugan et al. 2008).
When using HyPer5-dCTP for labelling, increasing the amount of dye in the reaction will increase yield of labelled targets desired for hybridization.
Probes specifically targeting desired gene of interest were ordered from the Nanostring Technologies (USA) who designed, synthesized and delivered the probes to the nCounter core facility at the Institute of human genetics, University clinic, Heidelberg, Germany.
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