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The target database contains 353 targetable human proteins with 385 binding sites.
DOCK6.0 is employed as the docking engine and the target database contains 353 targetable human proteins.
Qin, C. et al. Therapeutic target database update 2014: a resource for targeted therapeutics.
Yang, H. et al. Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information.
Nonfinancial competing interests include PubMed, TCM database@TW, SwissADME, DrugBank, Therapeutic Target Database, Cytoscape, UniProt and KEGG.
In sequence alignment, we want to associate residues in a query sequence with homologous residues in a target database sequence.
Pain disease proteins were collected from the Therapeutic Target Database and DisGeNET60 (with score >= 0.2, http://www.disgenet.org, version 5.0).
Zhu, F. et al. Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery.
The acquisition of such domain knowledge is crucial for the quality of the target database.
As a result 170 (13% of the target database) businesses used the free services on offer.
Physical level is used to choose a target database management system (DBMS) for implementing the logical model.
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