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It sacrifices some throughput gain for robustness and the satisfaction of the target constraints.
In light of this, we employ a general XML constraint model to define target constraints.
We recognize that target constraints play a crucial role in the generation of good solutions.
The synthesiser is designed for large population matrices and allows target variables to be represented in several target constraints.
Comparing the results of these varying scenarios provides insight on long-term strategies and the impact of target constraints on budget expenditures.
Considering the forecasted load curves provided by short term operation planning studies, an optimization problem is formulated to determine how many and which generating units should be dispatched in each hour and at which power plant so as to meet load, operational and energy target constraints.
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We consider a network where the communication between the source and the destination nodes follows an opportunistic protocol, namely, the relay is used whenever it allows with respect to the direct transmission: (a) for achievable rate improvements, under a power spectral density (PSD) mask constraint; or (b) for power saving, under a PSD mask and a rate target constraint.
In this study, we consider a network whose nodes have a PHY layer based on OFDM and where the communication between the source and the destination nodes follows an opportunistic protocol, namely, the relay is used whenever it allows (w.r.t. the DT): (a) for achievable rate improvements under a PSD mask constraint, or (b) for power saving under a PSD mask and a rate target constraint.
The small size, minimal targeting constraints, and modular regulation of Cas13d effectors further expands the CRISPR toolkit for RNA manipulation and detection.
These cleavage site and DNA spacer sequence dependencies enhance targeting specificity yet confer moderate targeting constraints.
The underlying biology of any genome-engineering reagent imposes design and targeting constraints (Halford et al. 2011).
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