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Results make it possible to provide deeper interpretation about the effectiveness of each feature for discrimination in target classes for query proteins.
The target classes for recognition can be either combinations of drums or detectors for each drum.
Another MLC solution that exploits dependencies between target classes for multi-label prediction is based on classifier chains (CC) [36].
It can be seen that performance varies widely across target classes: for most targets, including all aminopeptidases, calcium-dependent protein kinase 1, protein kinase Pfmrk, glucose-6-phosphate-1-dehydrogenase, dihydroorotate dehydrogenase, dUTP pyrophosphatase and enoyl-acyl-carrier protein reductase, performance is low, with both recall and precision values below 30%.
Following the clinical validation of this strategy with histone deacetylase (HDAC) inhibitors (Prince et al., 2009), writers, readers and erasers of histone marks constitute emerging therapeutic target classes for a variety of disease conditions.
It has been argued that epigenetic mechanisms are at the heart of cancer biology [ 9], and it is reasonable to ask whether protein families that control epigenetic signaling represent promising target classes for cancer prevention and treatment.
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In class CGTarget, a base target class for code generation, there are two CodeStreams: myCode and procedures.
In Fig. 4, we have three likelihood matrices corresponding to each target class for each test file.
Protein-protein interactions (PPIs) are broadly recognized as an emerging target class for a whole new era in drug discovery.
Fig. 5 Heat map showing clustering of SiteHopper PatchScores within proteins of the same target class for potential binding sites of a HIV-1 Protease, and b prothrombin.
Hence, the number of intervals obtained for attributes under question may be different depending on the number of possible cut points, the relation with the target class, for instance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com