Exact(1)
The first target captures visual attention.
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Rohland, N. & Reich, D. Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture.
Meyer, M. & Kircher, M. Illumina sequencing library preparation for highly multiplexed target capture and sequencing.
Shen, P. et al. Multiplex target capture with double-stranded DNA probes.
Conclusions: Our target capture design fills a major gap left by all other assays that exist to map DNA methylation.
It was that one moment where everything came together – good intel, the police commissioner present, eager press riding shotgun, the target captured and arrested.
Assays to target, capture, enrich or partition disease-specific regions of the genome offer immediate solutions for reducing the complexity of the sequencing libraries.
Target capture and library construction were performed using the protocol described in Hiatt et al.25 with modifications during library amplification.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com