Sentence examples for target bid from inspiring English sources

Here we demonstrate death receptor-independent cleavage of caspase-8 and -10 as well as downstream target Bid following treatment with Mcl-1 DsiRNA and ABT-737 (Figure 5).

Interestingly, similar system based on isolated mitochondria was also used to characterize compounds designed to target Bid to treat disorders associated with the activation of such pro-apoptotic protein [ 18].

siRNA targeting Bid (Cat# L-004387-00), PUMA (Cat# L-004380-00) anon-targetinging control siRNA (Cat# D-001810-01-05) were purchaseDharmaconarmacon (Lafayette, CO, USA).

The pLKO.1 vector was used to express shRNA targeting Bid.

Targeting BID, however, is rarely discussed, although such work has potential for use in combined therapy [ 34].

Calpain may also mediate apoptosis in endothelial cells by directly targeting Bid and apoptosis inducible factor [ 57].

Targeting BID by small molecules has been proposed as a way to treat immune-mediated inflammatory disease including inflammatory bowel disease.

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Bim−/−/Puma−/− MEFs expressing shRNA targeted against Bid also died at rates similar to controls (Figure 5C).