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Set within the context of metabolic networks, predicted using genome-wide reconstructions of metabolism, new hypotheses on how to target aspects of metabolism to design new drugs against these protozoa are emerging.
While these new probes may specifically target aspects of the apoptotic pathway, they do not address the ultrastructural changes upon which the term apoptosis was originally defined.
Firstly, on a bio-molecular level, antimicrobial development needs to be aggressive and target aspects of the pathogens which are least likely to have variable phenotypes.
These considerations are especially important in the development of anti-fibrotic and anti-cancer therapies, which might be able to target aspects that are dysregulated in both types of disease.
An analogous and other good example is presented in [ 72], where they used a protoplast assay to identify effectors that target aspects of flg22-induced immunity, including MAP kinase activation and gene expression.
Interventions that enhance patient-physician communication 45 or that help patients to cope with the two week waiting period before their pregnancy test 46 target aspects of treatment known to be particularly demanding and could help maintain quality of life during treatment.
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OMMPS and OKMMPS are more robust to the variation of target aspect than MMC method.
(3) OMMPS and OKMMPS are more robust to the variation of target aspect than MMC method.
However, HRRP is sensitive to target aspect, time-shift, and amplitude-scale.
It is obvious that the variation of target aspect becomes large when the number of HRRPs increases.
In this experiment, we consider the robustness of MMC, OMMPS, and OKMMPS to the variation of target aspect.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com