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This article provides a review of the literature describing evolving concepts in the treatment of early RA, studies that evaluate treatment strategies using a predefined target, and methods to identify patients who are at higher risk for progressive joint damage.
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In terms of both its chosen target and method, the Berlin attack has echoes of the slaughter brought to the French coastal city in July by a Tunisian-born French resident.
Although there has been no claim of responsibility, analysts and US counter-terrorism officials – including CIA director John Brennan – also said the choice of target and method of the attack bore hallmarks of Isis, which earlier this year bombed an airport and metro in Brussels, targeted Paris last year, and has been blamed for several attacks on Turkey in the past year.
Biosensor technology, a prominent technique for preliminary screening of the toxicity of samples, can be defined as having a sensing element for the selective detection of a target and method to transduce the interaction as a measureable signal.
If the party's agenda remains murky, its targets — and methods — are well known.
Teacher interpretations also inspire teachers to adopt particular learning outcomes, content, teaching strategies, and assessment targets and methods rather than others.
The specific falls in crime produced by improvements in security alongside their associated diffusions of benefit (preventive effects spilling out beyond the operational range of measures) to other targets and methods of committing crime are not matched by equivalent displacement".
Recent advances in immunoliposome design include rapid selection of phage antibody-derived scFv for targeting, and methods for conjugation of ligands to existing US Food and Drug Administration-approved liposomal drugs such as pegylated liposomal doxorubicin (Doxil/Caelxy [PLD]).
A better understanding of these analgesic pathways may allow us to identify new targets and methods for producing effective pain relief.
This could increase accountability by allowing stakeholders to understand rationales for selecting targets and methods.
Table 3 outlines the specific outcome areas that will be targeted and methods to examine outcome.
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