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According to the experimental observations, the non-Faraday material loss increases with flow velocity but decreases with surface hardness of the target, indicating a role of mechanical force.
This observation suggests that NFAP does not interfere directly with the activation of MpkA, but may affect a CWI pathway-independent MpkA-activated unknown target playing a role in the antifungal effect of NFAP.
In most drug discovery projects, a therapeutic target playing a role in a given disease is searched for, and once identified, the corresponding pathways can be identified.
Furthermore, FtsH was proposed as a candidate drug target, and a role was inferred for PhoU-mediated persister formation in S. aureus drug tolerance.
Those patients who engaged the right IFG more during Target-after-Neutral stimuli responded faster to targets, confirming a role of this region in coping with emotional distraction.
IPA analysis for targets of miR-221/222 showed that these targets play a role in regulating tumor morphology.
Mukherjee, C. et al. Identification of cytoplasmic capping targets reveals a role for cap homeostasis in translation and mRNA stability.
In fact, NadA has been described so far as having mainly epithelial targets, with a role in the colonization/invasion of the epithelial barrier.
► Many of the potential FXR targets have a role in regulating mitochondrial function.
Prior studies suggested that additional MP targets with a role in flower primordium initiation remain unidentified (Yamaguchi et al., 2013).
Increasing evidence points to the fact that epigenetic targets have a role in the molecular manifestation of stress and related disorders.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com