Exact(2)
"The concern I'd have is that when you have an approach where it's about reaching a quota or a certain number, but it becomes an official target, a requirement, then you'd always run this risk that someone might try to fill that just for the sake of filling it.
Targeting is complicated to an extent by a general requirement for thymine to precede the DNA target, a requirement of TALENs to bind paired opposing sites separated by a defined range of distances, differential contributions of different repeat types to overall affinity, and a polarity to mismatch tolerance.
Similar(58)
Administrators of the risk pools, which are formally called Pre-existing Condition Insurance Plans, point to a variety of explanations for low enrollment: lack of awareness among a hard-to-reach target population, a requirement that applicants be uninsured for at least six months and premiums that, although set at market rates, are often unaffordable.
miRNAs recognize target sequences usually in the 3'-UTRs of target mRNAs with a requirement for a nearly perfect match between the 5'-proximal 'seed' region (position 2 8) of the miRNA and its target mRNA for binding specificity [7], [8].
Clearly, robust amplification of a single target will be a requirement for future soybean TILLING.
In recent months, GPs at Clover had started assisting more closely with the summarising process, the aim being that Clover would achieve a 'higher percentage of notes summarised' (itself a QOF target, and also a requirement of GP training practices).
Furthermore, with evidence demonstrating variation in target delineation between expert clinicians, there is a need for specialized training that includes competencies such as anatomical knowledge and target delineation as a requirement of the radiation oncology postgraduate medical education curriculum [ 17- 20].
The aforementioned publication describing microsatellites as EWS-FLI1 targets pointed out a requirement for minimal length of four GGAA repeats for binding.
In addition, we provide mechanistic detail underpinning Pum-Brat repression of target mRNAs by showing a requirement for deadenylases.
13 In 2008, this target was replaced by a requirement for each primary care trust to report breastfeeding rates at 6 8 weeks and deliver local improvements.
Furthermore, it was found that restimulation with anti-CD3 antibodies was essential for target cell lysis, indicating a requirement for specific T cell receptor stimulation.
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