"tap function" is correct and usable in written English.
It is typically used to refer to a specific function or feature on a device or machine that involves tapping or touching it in some way. Example: "The new smartphone has a tap function that allows you to quickly switch between apps by tapping on the edge of the screen."
Peptide epitopes governed by an ER-signal sequence (ss) can bypass the requirement of TAP function to be transported into the ER lumen where the peptides are cleaved to remove the signal sequence for MHC-I binding [21] [23].
TAP function is dependent on ATP in order to complete a cycle of peptide translocation.
These results suggest that tap function, although dispensable for fertility in Drosophila, is required for transposon repression in germline cells.
We examined whether tap function is also required for localizing other nuage components to the nuage and vice versa.
Importantly, Qdm processing strictly depends on TAP function, which transports the proteasome-trimmed leader peptides into the ER [ 36].
Restoration of TAP function by gene transfer of TAP subunits or by IFN-γ treatment significantly decreased recognition of target cells by these CTLs.
TAP functions to transport cytosolic-generated peptides into the lumen of the endoplasmic reticulum (ER) for MHC-I binding, followed by transport of MHC-I/peptide complexes to the cell surface for T cell recognition.
Our results suggest that Tap functions synergistically with Tej in a complex to promote proper germline development and piRNA production.
Although the tap functions in the piRNA pathway, a milder derepression of transposons and milder decrease in piRNAs indicate it probably does not have a robust role in the piRNA pathway.
Furthermore, Myc-Piwi expressed from a native promoter in addition to endogenous Piwi in tej 48 5 -tap 125 double-mutant germline cells remained in the cytoplasm, whereas it localized to the nucleus in the somatic follicle cells, suggesting that simultaneous impairment of tej and tap functions prevents Piwi from entering the nucleus in germline cells.
The Piwi expression levels in tej 48 5 -tap 125, tej 48 5 and tap 125 mutants were found to be comparable to those in respective heterozygotes by western blot analysis, suggesting that loss of tej-tap function together leads to Piwi mis-localization without affecting its expression level.
