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The segmental duplication was ~13.5 kb in total and consisted of three equal tandem segments each with a single D1 gene and its flanking regions.
Such problems are exacerbated in regions containing identical or almost identical tandem segments which pose particular problems for both sequencing and assembly.
They exhibit tandem-segment mixed duplication model.
The second way is segment-tandem-segment duplication.
One of them is tandem-segment-tandem duplication.
In this model, genes from a tandem array were clustered together and no clade was detected with members from both tandem arrays, exhibiting a tandem-segment separated duplication model.
Evolution of tandem repeats is dominated by tandem segmental duplications resulting in regions composed of a highly variable number of almost exact copies of a short segment.
This gene duplication occurred as a result of tandem and segment duplications.
In vitro stability of M. mycoides subsp. mycoides SC strains with respect to the tandem repeated segment was tested by growing three selected strains in standard mycoplasma medium.
Chung et al. generated mice with a deletion of nine immunoglobulin-like domains from the proximal tandem immunoglobulin segment of the titin spring region, which resulted in overall titin stiffness [ 6].
Tandem repeat segments could be moved by recombinational excision of looped-out modified rDNA segments during meiotic unequal alignment of the rDNA repeating units and might re-integrate into a new location [ 17, 28].
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