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Thus, inhibition of ACL and activation of AMPK by ETC-1002 represent a unique tandem of complementary activities aimed to correct imbalances in lipid and carbohydrate metabolism.
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The rolling circle DNA synthesis created a long single stranded product consisting of tandem repeats of the complementary sequence of the original oligonucleotide, which was too long to enter the gel-matrix and could therefore only be visualized as a dot in the gel slot.
Emotion and motion, though seldom studied in tandem, are complementary aspects of social experience.
Similarly, in order to produce a miR-21 sponge vector, annealed double strands containing 8× tandem of binding sites that are perfectly complementary to miR-21 seeding sequence, was generated [ 23].
(4) An important piece of complementary information may be obtained through the use of tandem mass spectrometry,(5) whereby molecules of predetermined masses are fragmented through collision-induced dissociation.
It appears that the necessity of simultaneous amplification of complementary strands of double-stranded DNA can justify the existence of tandem replication complexes in the case of DNA polymerase; this rationale is lacking in the case of RNA polymerase, which utilizes only one DNA strand as a template.
In its simplest form, the SSM model involves local denaturation and displacement of the strands of a DNA duplex, followed by mispairing of complementary bases at the site of an existing similar sequences or short tandem repeat.
Tandem duplications may also be the consequence of an alternative NHEJ process that includes direct fill-in of complementary ends, followed by ligation of double-stranded ends (Roth et al. 1985) (Fig. 5 c ).
The circularised padlock probe is then amplified by a φ29 polymerase in the presence of dNTP's, producing a greatly elongated single-stranded DNA containing numerous copies of repeat tandem sequence units complementary to the circular padlock probe.
We are commanding officers of complementary companies.
The economist Joseph Farrell called this the "internalization of complementary efficiencies".
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