Building on prior work, Cott and colleagues (2002) compared walking and talking in pairs (30 minutes 5 times per week for 16 weeks) to talking alone (conversation in pairs) and no-intervention.
Women were literally getting arrested just for wearing pants in America as recently as the early 1900s, and we're not even talking about pairing them with jackets that have padded shoulders and lapels.
As he talks, a pair of his students practise their latest routine, accompanied by the school's star guitarist, Joni Jiménez.
FRPs were considered as putative pathway cross-talk pairs.
Therefore, PEBA identified 4,093 putative pathway cross-talk pairs among 167 pathways (Additional file 5). Figure 2 depicts the overlap between the predicted pathway cross-talks pairs of function-based approach (FBA) and physical entity-based approach (PEBA).
Because PID does not comprehensively collect pathway interactions, many well-known pathway cross-talk pairs are not curated into PID.
The distributions of co-expression values of putative pathway cross-talk pairs are given in Figure 3.
Huang et al. built a naïve Bayes classifier integrating properties of PTM cross talk pairs predicting cross talks for pairwise combination of PTM sites [ 16].
This is not surprising, since the common pairs that pass the criteria of the two distinct approaches are the most reliable pathway cross-talk pairs.
To evaluate the performance of the different method, 143 pathway interacting or cross-talk pairs were extracted from PID as positive data sets.
These two methods are complementary to each other, so they should be taken together to find all putative pathway cross-talk pairs, and we denote these two methods as the physical entity-based approach (PEBA).
