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The statistical model included fixed effects of flock, sex, DOB (date of birth), birth type, rear type and a random effect of animals (taking pedigree relationship into account).
In this study, the forward evolutionary simulation tool ForSim[ 18] was used to simulate genetic data taking pedigree structures and evolutionary processes (such as natural selection, mutation rate and population demographics) into account.
The process for patients referred for genetic assessment was similar in both centres: family history taking, pedigree construction, confirmation of cancer diagnoses in affected relatives, risk assessment, genetic counselling with advice on preventive strategies and, if appropriate screening, prophylactic surgery, and/or genetic testing.
The referred family was subjected to history taking, pedigree analysis, full clinical examination, and photography.
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JOE NAHEM is known for taking pedigreed 20th-century French designs by, say, Émile-Jacques Ruhlmann or Jean Royère and mixing them with anonymous pieces, but for his own house he did not go for big names.
findhap was originally designed for genotype imputation in livestock and takes pedigree information into account.
Moreover, we used Beagle for phasing, whereas Huang et al. used AlphaImpute [ 17], which can take pedigree information in consideration.
According to the recommendations made by Teyssedre et al. [ 6], data were analyzed using a mixed model that takes pedigree kinship into account.
As indicated in our introduction, this work was inspired by Thornton and McPeek [ 25] who offer two ways to analyze genetic associations: 1) using the standard χ statistic with a correction factor that takes pedigree information into account; and 2) using a factor that corrects for the conditional probability of IBD sharing.
Full medical and family histories were taken, pedigrees were drawn, and an ophthalmologic examination was performed.
Never use a shoulder strap in the obvious way; instead, take a roomy bag with long straps – the Coach Bleecker Sling, for instance – but shorten the straps by gathering them in your hand, as if taking a pedigree puppy for a walk.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com