Exact(7)
No patient in the study was taking biologics.
This tendency was also demonstrated in our cohort of 265 rheumatoid arthritis patients taking biologics.
We assumed that patients taking biologics had more severe disease and were more likely to develop malignant diseases.
Data from biologic registries 23 28 44 and US claims databases 29455 indicate approximately 30% of patients taking biologics use them as monotherapy.
For patients still taking biologics, we determined if they had received a medical consultation in the previous year and what tests had been undertaken in the previous year.
On the contrary, the chance of developing cancer was reduced in patients taking biologics, in comparison with matched patients taking nbDMARDs only.
Similar(53)
Under the assumption of rapid accumulation (uptake at 0 h p.i. corresponds to the uptake at 1 h p.i ., the cumulative radioactivity in each tissue was calculated (MBq/h) taking biologic elimination and physical decay into account up to 24 h p.i. and afterwards only physical decay up to 400 h p.i.
As shown in Table 2, our recruited immunosuppressed adults include those with several autoimmune conditions who are taking biologic, non-biologic, or both classes or medication.
Participants taking biologic DMARDs had significantly lower mean wrist pain thresholds than participants not taking biologic DMARDS (4.5 ± 1.9 kg/cm2 vs. 5.8 ± 1.9 kg/cm; P = 0.01).
They are predominantly female (11/16) (Table 2) and taking biologic therapies (11/16).
Patients taking biologic DMARDs were more frequently RF- and ACPA-positive than patients not treated with biologic DMARDs.
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