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Kerri Mason from Billboard magazine wrote that the song "takes a structure usually reserved for breathy chanteuses the big-room trance vocal and adds the firepower of Jennifer Hudson".
The 3D structure of TIP47 showed that its carboxy-terminal portion takes a structure similar to the four-helix bundle of apolipoprotein E, which mediates binding to lipoproteins (Hickenbottom et al. 2004).
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Warshel told reporters after the announcement: "What we developed is a way which requires a computer to look and take a structure of a protein and eventually to understand how it exactly does what it does, like if you have an enzyme that digests food and the structure exists, you want to understand how this is happening.
While most approaches focus on the disorder property, Stein et al. took a structure based approach focusing on the fact that most motifs that are found in disordered regions will take defined structure(s) upon binding [ 88].
Take a structure of an aeroplane.
Take a structured, shapely, shimmery top and pair it with Trekky trousers or, as seen at Balenciaga, a more unexpected pencil skirt and — wham! — you've got yourself a future perfect suit for fall.
To elucidate the functional significance and consequence of the LRP5 G171V mutation in vitro, we took a structure-based approach to design 15 specific LRP5 point mutations.
For the design of the new analogs, we took a structure-based design approach based on the X-ray crystal structure of colchicine-tubulin complex (PDB: 4O2B) and computational docking analysis using the AutoDock Vina program.
Structural information about protein targets often aids drug development, so here we take a structure-based approach, combined with computational screening, to discover amyloid interacting compounds that reduce amyloid toxicity.
Instead, the most stable C1 structure of F−(H2O 3 optimized by semiempirical methods takes a planar structure similar to C3h.
While 4 takes a dinuclear structure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com