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Others do not have limits to the order of interactions, but in practice take very long time to detect higher order interactions in real data of GWAS.
While with big τ(t), system would take very long time to reach convergence, with very small τ(t), the system may be trapped in a local minimum.
Finally, after establishing unit and level rings, butterfly connections are set up. (For more details on Georoy procedures please refer to [11].) In P2P networks, the lookup procedure can take very long time when the size of the network increases.
Delay-tolerant (DTN) communications are thus the natural choice for a networking paradigm where nodes can be disconnected from the Internet for the majority of the time and exchange of data can take very long time.
However, normal skin biopsies are not always available, especially in patients with a high percentage of skin affected by deep burning, and the generation of large amounts of cultured keratinocytes may take very long time, with an associated risk for the patients' survival.
If the interactions between objects and agents are high, complexity will increase Response time These approaches don't have best response time if a component is deactivated and urgent activation is required then it might take very long time which is performance degradation Cost (in terms of money) These are hard to build and are very expensive as well.
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However, the process can take very long times on a single machine.
On ILSVRC 2010, it takes very long time to train 1000 binary classifiers.
the SVM-SGD algorithm deals with the imbalanced datasets for building binary classifiers, the SVM-SGD algorithms also takes very long time to train very large number of binary classifiers in sequential mode using a single processor.
It can be seen from Table 16 that the optimization process, done by both the commercial optimisation solvers and the proposed GA, takes very long time and the consistency of the solution quality is not very high.
However, the development of stable cell lines takes very long times (6 12 months), and the cost of cell culture is very high (Lai et al. 2013).
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